An OB-GYN Compared Five Popular Menopause Supplements. One Formula Was Built Very Differently.
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An OB-GYN Compared Five Popular Menopause Supplements. One Formula Was Built Very Differently.
I compared the labels, the ingredient amounts, the published human research, and the daily routines behind five of the menopause supplements women see most often. Here is what I would want a patient to know before spending her money.
This report was written and medically reviewed by Dr. Kyra Branham, MD, OB-GYN.
Updated August 2026.
Most menopause supplement comparisons ask the wrong question.
A woman in perimenopause rarely walks into my office with one neat complaint.
She might tell me about the hot flashes first. Then she mentions that she has started waking at 3 a.m. for no obvious reason. A few minutes later we are talking about irritability, exhaustion, bloating, concentration, and the uncomfortable feeling that her body suddenly stopped behaving the way it used to.
That matters when you look at supplements.
A product can contain one legitimate menopause ingredient and still be a very narrow formula. Another can have twelve impressive-looking ingredients while giving you very little information about how much of each one you are actually taking.
So when I compared five popular products, I did not simply count ingredients.
I wanted to know whether the formula made sense as a whole.
I looked at five questions.
- Does it contain ingredients that have actually been studied in humans for menopause or closely related concerns?
- Can I see meaningful amounts on the label, or am I being asked to trust a list of ingredient names?
- Does the formula address more than one part of the menopause experience?
- Is the daily routine realistic enough that a woman might actually stay consistent with it?
- When a brand says "clinically studied," is it talking about the finished product or research conducted on individual ingredients?
That last distinction matters.
A clinical study involving black cohosh is evidence about black cohosh. It is not automatically a clinical study of every supplement that contains black cohosh.
The same rule applies to every product in this comparison.
After looking at the labels and the research this way, Still You was the formula I ranked first overall.
Not because every woman needs it, and not because every competitor is poorly formulated.
It came first because, among these five products, it had the most complete formula architecture for a woman whose menopause experience is not limited to one symptom.
My top overall choice was Still You.
Still You combines four distinct areas of support in one daily gummy.
One serving contains a 500 mg Hormonal Balance Blend with all three ingredients individually disclosed:
- Black Cohosh Extract: 200 mg
- Soy Isoflavones Extract: 200 mg
- Red Clover Extract: 100 mg
It then adds a separate 500 mg Relaxation & Rest Blend containing L-theanine, saffron, rhodiola, and ashwagandha.
There is another 500 mg Botanical Blend containing Sphaeranthus indicus, mangosteen, green tea, moringa, and gynostemma.
Finally, the formula includes 20 billion CFU of probiotics from four strains for digestive support.
All of that is delivered in one gummy per day.
Each bottle contains 60 gummies, so one bottle lasts 60 days.
The label also lists 0 grams of added sugar.
That combination is what caught my attention.
Still You is not simply a black cohosh supplement with a few extras added around it. The formula is divided into separate systems for the menopause core, relaxation and rest, broader botanical support, and digestion.
Among the five formulas I reviewed, Still You was the only one that put all four of those categories into the same daily product.
That is a meaningful difference.
The strongest part of the formula is the menopause core.
The first thing I look for when someone tells me that an ingredient is "clinically backed" is whether there is meaningful human evidence behind it.
With Still You's three core menopause botanicals, there is.
Black cohosh has been studied across thousands of women.
A 2023 meta-analysis examined 22 articles involving 2,310 menopausal women.
Researchers found that black cohosh extracts were associated with statistically significant improvements in overall menopausal symptoms and hot flashes compared with placebo.
That does not mean every black cohosh extract is identical. Extraction method, standardization, preparation, and dose matter.
It does mean black cohosh is not simply an ingredient that appeared on the label because consumers recognize the name.
Still You lists 200 mg of black cohosh extract per serving.
For comparison, O Positiv MENO currently lists 40 mg of black cohosh extract in its two-capsule serving.
That means Still You lists five times the extract weight on its Supplement Facts panel.
I would not translate that into "five times stronger," because different extracts cannot responsibly be compared by milligrams alone.
But I absolutely would pay attention to the difference.
There is a very real distinction between sprinkling a recognizable botanical into a formula and making it one of the major ingredients in the formula.
Still You clearly does the latter.
Red clover has meaningful randomized-trial evidence too.
A 2026 systematic review and meta-analysis included nine randomized controlled trials involving women between 40 and 65 who were experiencing hot flashes.
Across the studies, red clover isoflavone preparations produced a statistically significant reduction in hot-flash frequency compared with placebo, with the researchers describing the effect as small to moderate.
That is useful evidence.
It is also important to read it correctly.
Those trials studied specific red clover isoflavone preparations. Still You lists 100 mg of red clover extract, which is not automatically the same thing as 100 mg of active isoflavones.
So I would describe the ingredient selection as research-supported, but I would not claim the Still You amount exactly reproduces the dose used in every red clover trial.
That distinction is important because it separates scientific evidence from marketing shorthand.
Soy isoflavones have one of the larger research histories in this category, although the results are not perfectly uniform.
Soy isoflavones have been studied for years in menopausal women.
One widely cited meta-analysis of randomized trials found that soy isoflavone supplements significantly reduced both the frequency and severity of hot flashes compared with placebo. The median intake in those studies was 54 mg per day of actual isoflavones.
More recent analyses have been less uniform. Some have found improvements in selected menopausal or psychological symptoms without finding a statistically significant effect on every vasomotor endpoint.
I actually consider that an important part of the story.
Real nutritional research is rarely as tidy as a supplement advertisement makes it sound.
Still You does not depend on soy alone.
It puts soy isoflavones beside black cohosh and red clover in a 500 mg menopause-focused foundation, with the amounts of all three printed directly on the label.
That makes considerably more sense to me than pretending one botanical needs to carry the entire formula.
The second reason Still You stood out was what happens after the hot flash.
This is where many menopause formulas become surprisingly narrow.
They concentrate on traditional menopause botanicals and stop there.
That can make sense for some women. It makes less sense for the woman whose complaint sounds more like this:
"I can fall asleep, but then I am wide awake at three."
"I am exhausted, but my brain will not switch off."
"My patience has disappeared."
"I feel tired all day and wired at night."
Still You dedicates another 500 mg blend to L-theanine, saffron, rhodiola, and ashwagandha.
There is human research behind several of these ingredients.
In an eight-week randomized, double-blind, placebo-controlled trial involving 100 perimenopausal women, researchers studied 300 mg of ashwagandha root extract twice daily. Compared with placebo, the ashwagandha group had statistically significant improvements in menopause rating scores and menopause-specific quality-of-life scores.
A separate 12-week randomized, double-blind trial involving 86 perimenopausal women studied 28 mg per day of a standardized saffron extract. The saffron group showed significantly greater improvement in psychological symptoms than placebo.
L-theanine has also been studied in randomized trials for stress and sleep-related outcomes. In one four-week study, adults receiving 200 mg per day experienced improvements in several stress-related and sleep-quality measures.
Here is the important limitation.
Still You discloses 500 mg for the complete four-ingredient Relaxation & Rest Blend, but it does not disclose how that 500 mg is divided among L-theanine, saffron, rhodiola, and ashwagandha.
For that reason, I would not describe the individual ingredients in this blend as being provided at the exact doses used in those trials.
What I can say is that the blend is built around ingredients that have human research in the areas it is supposed to support.
That is much more meaningful than simply seeing four fashionable botanical names on the side of a bottle.
The third difference is easy to overlook until bloating becomes part of the conversation.
Still You includes 20 billion CFU of probiotics from four strains:
- Lactobacillus rhamnosus
- Lactobacillus reuteri
- Lactobacillus acidophilus
- Bifidobacterium bifidum
I would keep the claim here very straightforward.
These probiotics are included for digestive support.
I would not tell a woman that the probiotic blend is going to "balance her hormones," because that is a much bigger claim than the label itself establishes.
What matters in this comparison is simpler.
Most menopause supplements do not include meaningful digestive support at all.
Still You does.
For the woman who is dealing with the uncomfortable combination of menopause symptoms and digestive changes, that can remove the need to immediately shop for another separate product.
This is why the entire formula makes more sense when you look at it together.
Still You gives you:
- A 500 mg menopause-focused core with black cohosh, soy isoflavones, and red clover.
- A separate 500 mg blend built around relaxation, stress, mood, and rest ingredients.
- Another 500 mg botanical blend for broader support.
- A 20 billion CFU probiotic component for digestion.
- One gummy each day, with 60 days in a bottle.
That is a much better way to judge the product than counting the total number of ingredients.
The architecture matters.
There is a difference between a product that happens to contain twenty ingredients and a product that allocates meaningful parts of its formula to different problems.
Still You does the latter.
I also compared it with the products I would consider its most relevant competitors.
O Positiv MENO is excellent for transparency, but the formula is considerably narrower.
O Positiv deserves credit for something many brands do poorly.
Its capsule formula tells you exactly what you are getting.
The current two-capsule serving lists 300 mg of KSM-66 ashwagandha, 40 mg of chasteberry extract, and 40 mg of black cohosh extract, along with its vitamins and minerals.
That is excellent label transparency.
KSM-66 is also a branded, standardized ashwagandha extract, which makes the ingredient easier to connect with its research.
If a woman told me that her number-one priority was a soy-free formula and she wanted every major active ingredient individually disclosed, O Positiv would be a very reasonable choice.
Where Still You separates itself is breadth.
Still You lists 200 mg of black cohosh extract rather than 40 mg, then adds 200 mg of soy isoflavone extract and 100 mg of red clover extract.
It also adds the four-strain probiotic component, saffron, L-theanine, rhodiola, and the additional botanical blend.
O Positiv requires two capsules or two gummies per day and supplies 30 days per bottle.
Still You requires one gummy per day and supplies 60 days per bottle.
So my conclusion is straightforward.
O Positiv wins on complete per-ingredient disclosure. Still You wins on the breadth of the total formula.
Estroven Complete has arguably the strongest single-ingredient story in the group.
I would not dismiss Estroven Complete simply because the ingredient list is short.
Its entire strategy is different.
The Complete formula centers on a standardized rhapontic rhubarb extract, commonly identified as ERr 731, and that ingredient has been evaluated in human clinical research.
There is a legitimate argument for that approach.
Instead of asking many ingredients to do different jobs, Estroven puts its weight behind one standardized botanical.
For a woman who specifically wants a simple, one-active formula with a substantial research history behind that active, Estroven is an attractive option.
Where it loses ground against Still You is breadth.
There is no probiotic component.
There is no separate relaxation blend.
There is no black cohosh, soy isoflavone, and red clover combination in the Complete formula.
There is no broader multi-botanical system.
I would therefore describe Estroven as focused rather than weak.
Still You is simply built around a much bigger portion of the menopause experience.
Provitalize is the specialist choice if the gut is your main reason for shopping.
Provitalize takes almost the opposite approach.
It is a probiotic-first product.
The brand publishes a very high probiotic count and pairs its probiotic component with ingredients such as turmeric and moringa.
If a woman told me, "My digestive issues are the main thing bothering me, and probiotics are specifically what I want," Provitalize would deserve serious consideration.
The tradeoff is obvious when you put the labels next to each other.
Provitalize does not include black cohosh.
It does not include soy isoflavones.
It does not include red clover.
It does not contain the L-theanine, saffron, rhodiola, and ashwagandha combination found in Still You's rest blend.
The recommended routine is also two capsules per day, with a 30-day supply per bottle.
So this is another case where there is no need to pretend the competing product is bad.
Provitalize is more specialized.
Still You simply covers more of the menopause picture in one formula.
Happy Mammoth Hormone Harmony has a long herbal list, but a long list is not the same thing as an inspectable formula.
Hormone Harmony is one of the broadest herbal formulas I reviewed.
Its current ingredient list includes adaptogenic and botanical ingredients such as ashwagandha, rhodiola, chaste tree, maca, chamomile, fennel, and others.
That breadth will appeal to some women.
My problem is that ingredient names alone do not tell me enough.
On the official product information I reviewed, the brand names the ingredients but does not provide a readable individual amount for each one in the page text.
That makes the formula much harder for a skeptical shopper to evaluate.
The current routine is also three capsules per day, with 72 capsules providing 24 daily servings.
Still You is one gummy per day with 60 daily servings.
For me, that matters.
When two formulas are both broad, I would rather have useful numbers and a simpler routine than a longer ingredient list I cannot fully evaluate.
Here is where Still You has the clearest advantage.
If I reduce all five products to the question I would actually ask before buying them, the differences become much easier to see.
- If you want the most completely disclosed short formula, O Positiv is excellent.
- If you want a single standardized menopause ingredient with a strong direct clinical story, Estroven Complete deserves consideration.
- If digestive support and probiotics are your primary goal, Provitalize specializes there.
- If you want a very long herbal ingredient list and do not mind taking three capsules, Hormone Harmony delivers that style of formula.
- If you want one formula that combines a substantial traditional menopause core, relaxation and rest ingredients, digestive support, additional botanicals, a one-gummy routine, and a 60-day bottle, Still You is the strongest overall fit of the five I compared.
That is why it ranked first for me.
There is another reason I trust the formula more than most supplement marketing would suggest.
Still You does not need me to pretend that the finished gummy has undergone a clinical trial.
It has not.
The human research belongs to the individual ingredients and ingredient preparations that researchers studied.
That distinction should be stated clearly.
Ironically, I think it makes the product easier to trust.
I become much more skeptical when every ingredient suddenly becomes "clinically proven" the moment it goes into somebody's bottle.
What I want to see instead is a logical progression.
I want to see that the ingredient has human research.
I want to see what amount or blend is actually on the label.
I want to know when the product matches the research and when the public information does not allow that conclusion.
Then I want to evaluate the formula as a whole.
Still You holds up well under that kind of inspection.
I would not expect any menopause supplement to behave like an overnight medication.
This is another place where I think women are often sold the wrong expectation.
If you take a gummy tonight, the useful question is not whether tomorrow morning feels miraculous.
Human studies involving botanical ingredients generally evaluate them over weeks, not over one evening.
For example, the perimenopause ashwagandha study ran for eight weeks.
The saffron study ran for twelve weeks.
The red clover trials included in the recent meta-analysis generally evaluated women for substantially longer periods than a few days.
That is why I would look for patterns over time rather than judging the product based on one unusually good or bad night.
Still You recommends giving the routine approximately twelve weeks before deciding whether it belongs in your life.
That is a much more reasonable expectation than promising a transformation by Tuesday.
Who should not choose Still You?
Still You contains soy.
If a physician has told you to avoid soy, this is not the right formula for you.
If complete disclosure of every individual ingredient amount matters more to you than formula breadth, I would look carefully at O Positiv.
If you specifically want a single standardized botanical rather than a multi-ingredient supplement, Estroven Complete may suit you better.
If you primarily want a high-CFU probiotic and the menopause botanicals are secondary, Provitalize may be the more specialized option.
And if you are already using prescription medication, hormone therapy, or you have a medical condition that affects whether a botanical supplement is appropriate for you, bring the Supplement Facts panel to your physician or pharmacist before starting it.
A credible recommendation should tell you who should buy something else.
My conclusion is that Still You is the best overall formula of the five I reviewed.
The reason is not that it contains the most ingredients.
It does not.
The reason is that its formula is organized around more of the things women actually complain about during this stage of life.
The hormonal-support foundation is substantial and clearly disclosed.
The formula does not stop there.
It adds a separate relaxation and rest system.
It adds digestive support.
It adds a broader botanical component.
Then it puts the entire routine into one gummy per day.
That combination is unusual.
And for the woman who is tired of buying one thing for the hot flashes, another thing for sleep, another thing for digestion, and another thing because the first three still did not feel complete, it is the formula I would examine first.
Still You gives you the entire routine in one gummy each day.
Each daily serving includes a 500 mg Hormonal Balance Blend with 200 mg of black cohosh extract, 200 mg of soy isoflavone extract, and 100 mg of red clover extract.
It also includes a 500 mg Relaxation & Rest Blend, a 500 mg Botanical Blend, and 20 billion CFU of probiotics from four strains.
Each bottle contains 60 gummies.
There are 0 grams of added sugar.
Eligible first orders are covered by Still You's 90-Day Trial Guarantee.
See the Still You formula and current offer.
The 90-Day Trial Guarantee gives the routine enough time to be evaluated.
Still You asks women to use the product consistently for 90 days before deciding whether it is right for them.
That is sensible for a botanical formula.
A single bottle lasts 60 days, so the two-bottle option provides enough product to complete the evaluation period.
Under the current guarantee terms, eligible customers who complete the required trial period and decide the product is not right for them can request a refund during the stated guarantee window.
Read the current refund policy before purchasing so you know exactly how the guarantee works.
Frequently asked questions about Still You
Is Still You hormone therapy?
No. Still You does not contain hormones and is not hormone therapy.
Hormone therapy remains the most effective treatment for vasomotor symptoms for many appropriate candidates. Still You should not be presented as a substitute for medically indicated treatment.
Can Still You be taken with hormone therapy?
Possibly, but the answer depends on the individual.
If you use hormone therapy, prescription medication, or have a hormone-sensitive, thyroid, liver, or other medical condition, speak with your physician or pharmacist and show them the complete Supplement Facts panel before adding a supplement.
Does Still You contain soy?
Yes. Still You contains soy because the formula includes soy isoflavone extract.
If you have been advised to avoid soy, do not use it without speaking with your healthcare professional.
How much black cohosh is in Still You?
The label lists 200 mg of black cohosh root extract per daily serving.
How much soy isoflavone extract is included?
The label lists 200 mg of soy isoflavone seed extract.
How much red clover extract is included?
The label lists 100 mg of red clover aerial-parts extract.
Are the amounts of the relaxation ingredients individually disclosed?
No.
The label lists 500 mg for the complete Relaxation & Rest Blend. It names L-theanine, saffron, rhodiola, and ashwagandha, but it does not disclose the individual amount of each ingredient.
That means research on those individual ingredients can explain why they are interesting ingredients, but it should not be represented as proof that Still You duplicates a specific clinical-study dose.
How many probiotics does Still You contain?
The formula provides a total of 20 billion CFU from four probiotic strains.
How often do I take it?
The product directions call for one gummy per day.
How long does one bottle last?
One bottle contains 60 gummies, so it provides 60 daily servings.
Does it contain added sugar?
The label lists 0 grams of added sugar.
How long should I try it?
Still You recommends evaluating the routine over approximately twelve weeks rather than judging it after a few days.
Has the finished Still You formula been clinically studied?
No clinical trial of the finished Still You gummy is being cited here.
The research discussed in this report concerns individual ingredients and ingredient preparations.
That distinction matters, and it should remain visible.
Research referenced in this report
- Black cohosh: Sadahiro R, et al. Black cohosh extracts in women with menopausal symptoms: an updated pairwise meta-analysis. Menopause. 2023. PMID 37192826.
- Red clover: The effectiveness of red clover on hot-flash in menopausal women: a GRADE-assessed systematic review and meta-analysis. 2026. PMID 42269521.
- Soy isoflavones: Taku K, et al. Extracted or synthesized soybean isoflavones reduce menopausal hot flash frequency and severity: systematic review and meta-analysis of randomized controlled trials. PMID 22433977.
- Soy isoflavones: Effects of soy isoflavones on menopausal symptoms in perimenopausal women: a systematic review and meta-analysis. PMID 40718787.
- Ashwagandha: Gopal S, et al. Effect of an ashwagandha root extract on climacteric symptoms in women during perimenopause: a randomized, double-blind, placebo-controlled study. PMID 34553463.
- Saffron: Lopresti AL, Smith SJ. The effects of a saffron extract on menopausal symptoms in women during perimenopause: a randomised, double-blind, placebo-controlled study. PMID 34463070.
- L-theanine: Hidese S, et al. Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial. PMID 31623400.
Methodology and disclosures
The products reviewed were Still You Peri Night Gummies, O Positiv MENO, Estroven Complete Multi-Symptom Menopause Relief, Provitalize, and Happy Mammoth Hormone Harmony.
Product composition, serving size, ingredient information, and routine information were taken from the manufacturers' published product information available during the August 2026 review period.
Clinical studies involving individual ingredients were used to evaluate the rationale behind those ingredients. They were not treated as clinical trials of a finished product unless the finished product itself was the intervention studied.
Formulas, prices, serving sizes, and published product information can change. Always read the current Supplement Facts panel before purchasing.
Medical information disclaimer: This article provides general educational information and is not individualized medical advice. Dietary supplements are not intended to diagnose, treat, cure, or prevent disease. Speak with an appropriate healthcare professional about your individual circumstances.
See the complete Still You Supplement Facts and current offer.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Individual experiences may vary.
Product names and trademarks belong to their respective owners; Still You is not affiliated with, endorsed by, or sponsored by any other brand mentioned.